Cardiovascular diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Volunteers who are being monitored at InCor / HCFMUSP; using oral anticoagulant (warfarin) only as the only medication capable of altering blood clotting and bleeding time; TP / INR (2.0-4.0), accepting to participate in the study; allow clinical examination; present bilateral upper permanent teeth with indication of extraction.
Exclusion criteria
Exclusion criteria: Patients with PT / INR outside the range defined by the study (2-4); patients using drugs such as antiplatelet agents in association with warfarin; with coagulopathies; with liver disease; with thrombocytopathies and thrombocytopenia; toothless upper patients; patients who do not have an indication for extraction; patients who do not accept to participate in the research for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Similar local hemostasis verified with the quantification of bleeding by means of gravimetry in mg in three moments: immediately after sutures, 72 hours and 8 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Best tissue repair, determined through the clinical repair scale at 72h and 8 days after suturing. | — |
Countries
Brazil
Contacts
Faculdade de Odontologia da Universidade de São Paulo;Faculdade de Odontologia da Universidade de São Paulo