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Evaluation of the efficacy of multiple stiches as a method of controlling local bleeding in patients using oral anticoagulants: randomized clinical trial

Evaluation of the efficacy of mass suture as a method of local hemostasis in patients using warfarin: randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-49hcnx
Enrollment
Unknown
Registered
2020-07-23
Start date
2020-08-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases

Interventions

Patients will be evaluated clinically by the researcher in the dental office of the InCor Dentistry Unit using a clinical mirror and explorer. Each patient should have two permanent upper and bilatera
Procedure/surgery
D27.505.954.502
E06.892

Sponsors

Faculdade de Odontologia da Universidade de São Paulo
Lead Sponsor
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Collaborator
Faculdade de Medicina da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Volunteers who are being monitored at InCor / HCFMUSP; using oral anticoagulant (warfarin) only as the only medication capable of altering blood clotting and bleeding time; TP / INR (2.0-4.0), accepting to participate in the study; allow clinical examination; present bilateral upper permanent teeth with indication of extraction.

Exclusion criteria

Exclusion criteria: Patients with PT / INR outside the range defined by the study (2-4); patients using drugs such as antiplatelet agents in association with warfarin; with coagulopathies; with liver disease; with thrombocytopathies and thrombocytopenia; toothless upper patients; patients who do not have an indication for extraction; patients who do not accept to participate in the research for any reason.

Design outcomes

Primary

MeasureTime frame
Similar local hemostasis verified with the quantification of bleeding by means of gravimetry in mg in three moments: immediately after sutures, 72 hours and 8 days.

Secondary

MeasureTime frame
Best tissue repair, determined through the clinical repair scale at 72h and 8 days after suturing.

Countries

Brazil

Contacts

Public ContactMariia;Sahar Naclério Hmomem;Ganz Riman

Faculdade de Odontologia da Universidade de São Paulo;Faculdade de Odontologia da Universidade de São Paulo

mgracanh@usp.br;sahar.riman@usp.br551130917911;5511983250128

Outcome results

None listed

Source: REBEC (via WHO ICTRP)