hypercholesterolemia
Conditions
Interventions
The trial will consist of 30 children who will be randomized and allocated in two groups of 15.
The intervention group will receive one capsule 800mg phytosterol before lunch and one 800mg phytosterol
Dietary supplement
E78.2
Sponsors
Hospital Universitário Pedro Ernesto
Hospital Universitário Pedro Ernesto
Universidade do Estado do Rio de Janeiro
Eligibility
Age
6 Years to 19 Years
Inclusion criteria
Inclusion criteria: Children and adolescents between 6 and 19 years old with LDL-cholesterol above 110mg / dL
Exclusion criteria
Exclusion criteria: Presence of heart disease, obesity, diabetes, nephrotic syndrome, systemic arterial hypertension, Down syndrome, Prader-Willi syndrome, hypothyroidism, Cushing's syndrome. Children and adolescents using lipid-lowering foods or medications such as corticosteroids, estrogens, progesterone, beta-blockers, and thiazides.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant reduction of LDL-cholesterol by the lipidogram at the end of the eighth week of intervention in the experimental group, with a reduction of five per cent in the intervention group.;Reduction in fasting insulin values, verified by the laboratory dosage at the end of the eighth week of intervention in the experimental group, with reduction of five per cent.;Reduction of systolic and diastolic blood pressure values, measured by electronic device calibrated and validated for research at the end of the eighth week of intervention in the experimental group, with a five per cent reduction. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactAna Karolina Moriel Tavares
Universidade do Estado do Rio de Janeiro
Outcome results
None listed