heart failure, coronary insufficiency, myocardial infarction
Conditions
Interventions
Intervention increased flow generated by the pump to bypass L/min/m2 3.0 to 3.5 during cardiopulmonary bypass in myocardial revascularization
Control flow generated by the extracorporeal pump 2.2 to
procedure/surgery
Sponsors
Instituto Nacional de Cardiologia
Maria aparecida Nogueira de Lima Marcondes Salgado
Eligibility
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patient admitted to the National Institute of Cardiology, which have coronary heart disease and were referred for surgery for isolated primary CABG, patients with ejection fraction greater than or equal to 45%, both sexes; aged between 18 and 75 years, during cardiopulmonary bypass use of vacuum-assisted venous drainage and use of normothermia during cardiopulmonary bypass
Exclusion criteria
Exclusion criteria: Patient admitted to the National Institute of Cardiology, which appear as disease and / or diagnosis associated with surgery, recent myocardial infarction (less than 3 months), recent stroke (less than 3 months, unstable angina, urgent or emergency surgery, diabetes mellitus decompensated - disease of diabetic ketoacidosis, renal failure - creatinine clearance <30 ml / min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decline in value of lactate during cardiopulmonary bypass in at least 30%. Normal value of lactate less than 3 mmol / L | — |
Secondary
| Measure | Time frame |
|---|---|
| The oxy-hemodynamic variables, oxygen delivery (350 to 450 mL/min/m2), oxygen consumption (90 mL/min/m2), mixed venous oxygen saturation (70 to 80%), venous blood carbon dioxide gradient carbon (less than 10 mmHg) and arteriovenous difference of pH (less than 0.1), must be within these values ??so that tissue perfusion is adequate. | — |
Countries
Brazil
Contacts
Public ContactMaria Marcondes Salgado
Instituto Nacional de Cardiologia
Outcome results
None listed