The effect of toothpaste with active oxygen in reducing of dental plaque.

The effect of active oxygen on dental dentifrice in reducing supragingival biofilm: randomized clinical trial

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

REBEC

Registry ID

RBR-48mvdx

Enrollment

Unknown

Registered

2016-12-16

Start date

2016-06-16

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis, Periodontal Disease

Interventions

It will take 48 students of dentistry for the study aged between 18 and 35 years. These volunteers should be 7 to 10 days without brushing their teeth to develop gingivitis. After gingivitis establish

Other

E05.318.308.980.438.300.300

V02.550

D25.376.711

Eligibility

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; aged between 18 and 35 years; a minimum of 28 teeth; no dental cavities; no periodontitis and established gingivitis.

Exclusion criteria

Exclusion criteria: antibiotic therapy three months before the study, using braces, motor difficulty, smoking and lack of commitment to the study

Design outcomes

Primary

Measure	Time frame
Low plaque scores after using the toothpaste containing hydrogen peroxide, sodium perborate, honey, xylitol and lactoferrin, observed by plaque indice.	—

Secondary

Measure	Time frame
Reduction of sites with gingival bleeding observed by scores of Gingival Index.	—

Countries

Brazil

Contacts

Public ContactCarmen Storrer

Universidade Positivo

carmen.storrer@gmail.com+55 41 33173454

Outcome results

None listed

Source: REBEC (via WHO ICTRP)