Binge drinking
Conditions
Interventions
Intervention Group: 59 participants in this group should ingest, orally, 1 capsule of omega-3 every 8 hours, that is, 3 capsules a day, for 3 months. The omega-3 capsules contained 1 g of fish oil, wi
0.5g protein
1.5g of total fat
0.5g of saturated fats
0.33g of monounsaturated fats
0.65g of polyunsaturated fats
376mg of eicosapentaenoic acid (EPA) and 250mg of docosahexaenoic acid (DHA).
Placebo Group: 52 participants in this group should take, orally, 1 placebo capsule every 8 hours, that is, 3 capsules a d
zero carbohydrates and proteins
12g of total fat
2.5g of saturated fats
5.2mg of vitamin E
zero trans fat
dietary fiber and sodium.
All participants underwent a medical screening interview to confirm that the participant met all the inclusion criteria and signed the Informed Consent Form. After this scree
Obsessive-Compulsive Drinking Scale
Penn Alcohol Craving scale
Short Alcohol Dependence Data. This entire assessment procedure took about 1 hour and a half.
Participants were evaluated 1, 2 and 3 months after the start of the intervention. An attempt was also mad
D10.212.302.380.410.385
Sponsors
Universidade Federal de São Paulo
Associação Fundo de Incentivo à Pesquisa
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Male; age between 18 and 70 years; severe alcohol use disorder according to DSM-5 criteria (Diagnostic and Statistical Manual of Mental Disorders 5th. edition)
Exclusion criteria
Exclusion criteria: Volunteers with a history of allergic processes to fish; severe pathological history of hepatic, cardiovascular, renal, pulmonary, endocrine, neurological and psychiatric disorders with psychotic symptoms such as schizophrenia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: To verify the possible reduction in the number and intensity of relapses in alcohol-dependent patients who received omega during 3 months of hospitalization, using the Timeline Followback questionnaire, pre-intervention and post-intervention.;Outcome found 1: the group that received omega consumed alcohol in fewer days, compared to the control group, in the evaluation of two months after the start of treatment and three months after the start of treatment, using the Timeline Followback questionnaire, comparing the baseline measurement (pre-intervention) with the measurement after 1, 2 and 3 months of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety symptoms were evaluated based on the score obtained by completing the Beck Anxiety Inventory questionnaire, comparing the pre-intervention and post-intervention scores. No statistically significant differences were found.;Symptoms of depression were evaluated based on the score obtained by completing the Beck Depression Inventory questionnaire, comparing the pre-intervention and post-intervention scores. No statistically significant differences were found. | — |
Countries
Brazil
Contacts
Public ContactJosé Galduroz
Outcome results
None listed