Breast Cancer
Conditions
Interventions
Intervention: application of erector spinal block guided by ultrasound with 20ml ropivacaine 0.75% in 50 patients under general anesthesia who will undergo unilateral mastectomy and axillary lymphaden
Procedure/surgery
Sponsors
AC Camargo Cancer Center
AC Camargo Cancer Center
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients older than 18 years; female; to be submitted to mastectomy with lymphadenectomy and unilateral breastl reconstruction (prosthesis or expander); described surgeries taking place at AC Camargo Cancer Center; no history of allergy to any medication used in the study; absence of contraindication to the regional block (coagulopathy and / or local infection); acceptance to participate in the study.
Exclusion criteria
Exclusion criteria: Patients who require a new surgery within 6 months after mastectomy; patients to whom we cannot contact in periods of 3 and 6 months post surgery; patients who require radiotherapy treatment; patients in which occur block failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower morphine consumption among patients exposed to the block when compared to those not exposed, through total morphine consumed in the hours after surgery. • Average morphine consumption between exposed cases: 1%. • Average morphine consumption among unexposed cases: 1.5%. • Significance level: 5%. • Test power: 95%. • Sample size calculated for each group: 46 In order to evaluate a possible difference in the pain intensity between the anesthetic techniques used, the Mann-Whitney U test will be applied. Analysis will be performed using SPSS software version 23 and software R version 3.4 | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactEduardo Sakai
AC Camargo Cancer Center
Outcome results
None listed