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Respiratory system evaluation in treatment of acute pulmonary exacerbation in children and adolescents with Cystic Fibrosis

Evolution of respiratory system evaluation parameters after treatment of acute pulmonary exacerbation in children and adolescents with Cystic Fibrosis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-489ww6
Enrollment
Unknown
Registered
2019-03-04
Start date
2018-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis

Interventions

24 Children and adolescents with cystic fibrosis who are hospitalized for treatment with intravenous antibiotics (IVA) due to acute pulmonary exacerbation will be included. Data collection will occur
Other
J44.1

Sponsors

Universidade do Estado de Santa Catarina
Lead Sponsor
Centro de Ciências da Saúde e do Esporte
Collaborator

Eligibility

Age
1 Months to 15 Years

Inclusion criteria

Inclusion criteria: Children and adolescents with CF; from one month to 15 years of age; hospitalized to IVA for treatment of acute pulmonary exacerbation; oriented; collaborative, in the case of children older than five years; and without neurological deficit; without auditory deficit; without visual deficit; they may not be in invasive mechanical ventilation support.

Exclusion criteria

Exclusion criteria: Children / adolescents who are unable to perform or terminate spirometry; unable to perform or terminate IOS; unable to perform or terminate functional/exercise capacity tests; requiring surgical intervention; requiring ventilatory support.

Design outcomes

Primary

MeasureTime frame
Primary outcomes: pulse oscillometry parameters (IOS), presented in kilopascal-kPa and percentages of predicted. Will be performed at moments before, during and after admission to IVA. ;Spirometry parameters presented in liter (L), liter per second (L / s) and percentages of predicted. Will be performed at moments before, during and after admission to IVA.;Performance on functional / exercise capacity assessment tests (total number of repetitions in the sit and stand test, total time of the step test). Will be applied at the beginning and at the end of the hospital stay.—

Secondary

MeasureTime frame
Secondary outcomes: score of clinical scores for acute pulmonary exacerbation (CFCS and CFFS) and anthropometric data (mass in kilograms-kg, height in meters-m and BMI in kg/m 2). They will be evaluated the moments before, during and after admission to IVA.—

Countries

Brazil

Contacts

Public ContactTayná Castilho

Centro de Ciências da Saúde e do Esporte

taynacastilho@hotmail.com+55-048-999469417

Outcome results

None listed

Source: REBEC (via WHO ICTRP)