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Reduction of postoperative pain in knee ligament surgery: morphine versus femoral block

Postoperative Analgesia: Intrathecal Morphine versus Femoral Block

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
REBEC
Registry ID
RBR-4897pw
Enrollment
Unknown
Registered
2019-08-14
Start date
2013-12-03
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament injury of the knee.

Interventions

The patients were divided into 4 groups equally submitted to spinal anesthesia with 15 mg of 0.5% isobaric bupivacaine, for which a tramadol 50mg EV of 6 / 6h, a salvage opioid, was added to the immed
Drug
Procedure/surgery

Sponsors

Hospital Universitário Cajuru
Lead Sponsor
Hospital Universitário Cajuru
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients submitted to elective surgery using the technique of anatomical reconstruction of the ACL with flexor tendons (semitendinous and gracilis); age between 18 and 65 years; classified as ASA I or II; score of at least 15 on the Glasgow Coma Scale; with the capacity to correctly answer the questionnaire applied by the researcher; who signed the informed consent term.

Exclusion criteria

Exclusion criteria: Patients who did not meet the inclusion criteria; presence of other painful complaints that could confound the postoperative evaluation; sensory or motor neurological deficit of the lower limbs; infection at the puncture site; previous coagulopathies and / or INR less or equal 1.5; with another contraindication to the proposed technique; history of allergic reaction to some of the drugs used in the studies; patients with diabetes mellitus due to the increased probability of previous neuropathy due to the disease.

Design outcomes

Primary

MeasureTime frame
Postoperative pain intensity was assessed at 6, 12 and 24 hours post-operatively using the numerical visual scale (NVA) between 0 and 10.;There was no statistically significant difference in the intensity of postoperative pain among the four groups analyzed.

Secondary

MeasureTime frame
The need for postoperative rescue opioids, adverse reactions such as nausea and vomiting, pruritus and urinary retention, occurrence of falls and patient satisfaction with the proposed technique were evaluated.; It was observed a greater occurrence of urinary retention in the subarachnoid morphine group and a greater occurrence of prolonged motor block of the quadriceps muscle in the group where the femoral nerve block with ropivacaine was performed at 0.37%, with no difference the other evaluated outcomes.

Countries

Brazil

Contacts

Public ContactJoana Fiorentin

Sianest - Anestesia Florianópolis

joanafiorentin@yahoo.com.br5504832235323

Outcome results

None listed

Source: REBEC (via WHO ICTRP)