Vomiting
Conditions
Interventions
Experimental Group 1 (EG1): 16 women given cervical cancer treatment with Cisplatin associated with radiotherapy will receive capsules containing 250mg of the ginger extract contained in capsules, ing
Sponsors
Liga Norte Riograndense Contra o Câncer
Liga Norte Riograndense Contra o Câncer
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Over 18 years old; have a diagnosis of cervical cancer with histological confirmation; have an indication for treatment with cisplatin 40mg/m² weekly associated with radiotherapy; preserved capsule swallowing capacity
Exclusion criteria
Exclusion criteria: Have a history of hypersensitivity to ginger; pregnancy or breastfeeding; have another primary neoplasm; ongoing chemotherapy treatment; having undergone previous antineoplastic and/or radiotherapy treatment; radiotherapy treatment in the epigastric region of the abdomen; surgery scheduled during the study period; have any feeding device (nasoenteric tube, gastrostomy, or jejunostomy); in simultaneous use of a supplement or ginger-based foods; using anticoagulants; have a history of bleeding disorders (severe thrombocytopenia), hyperthyroidism, and heart disease; a pre-existing condition causing nausea and vomiting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the reduction of nausea and vomiting using the Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 scale adapted for nausea and vomiting. In this way, it is possible to measure the intensity and intensity of events. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the quality of life of patients using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ C30) and EORTC quality of life cervical cancer module (EORTC QLQ Cx24). With these instruments it is expected to analyze the interference of the treatment in the quality of life, as well as the influence of ginger in its improvement. | — |
Countries
Brazil
Contacts
Public ContactRomeika Lorena da Silva
Outcome results
None listed