Transsexualism
Conditions
Interventions
The study is presented as a randomized pilot study blinded to the researcher and statistician. A total of 40 people can be used to allow another intervention group to be used and be a computer generat
while group 2 (T0): participant will discontinue the use of testosterone due to erythrocytosis. Data collection and application of questionaires will occur 11 week after recruitmeant. Pre and post-int
D06.472.334.851.968.984
Sponsors
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Transgender men with and with a diagnosis of testosterone-induced erythrocytosis will be included.
Exclusion criteria
Exclusion criteria: Male transgender (MT) with polycythemia vera or secondary to other pathologies (chronic kidney disease, severe lung disease, chronic myeloid leukemia, lymphoma, liver diseases and Cushing's syndrome); MT using hormonal contraceptives or copper IUDs; MT with psychiatric conditions such as severe psychotic disorders, severe personality disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find hematocrit reduction to less than 50% with dose reduction for 3 months in these patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a more favorable bleeding pattern (amenorrhea or infrequent) with fractional dose prescription compared to drug withdrawal at 3 months.;It is expected to find an anxiety and depression score with fractional dose prescription compared to drug withdrawal at 3 months.;It is expected to find maintenance of normal hormones with fractional dose prescription compared to drug withdrawal at 3 months.;It is expected that no biochemical alterations will be found between the MDs who used the fractionated dose and those who discontinued the use of testosterone cypionate during the three months of intervention. | — |
Countries
Brazil
Contacts
Public ContactSergio Pires Okano
Faculdade de Medicina de Ribeirão Preto
Outcome results
None listed