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Evaluation of a gel containing green tea and hyaluronic acid after periodontal access flap surgery: randomized clinical trial

Evaluation of a gel containing the active ingredient of green tea and hyaluronic acid in post-surgical tissue repair: a randomized clinical study in humans

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-475mc4q
Enrollment
Unknown
Registered
2024-06-06
Start date
2023-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

This is a double-blind randomized controlled clinical study. Experimental group: 25 patients with periodontal disease but without systemic diseases who will receive surgical periodontal therapy and a

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both sexes; should have completed periodontal therapy related to the cause more than a month ago and still have sites with 2 or more adjacent teeth presenting pockets with a probing depth greater than or equal to 5 mm; with bleeding on probing and/or suppuration; and also good standards of oral hygiene (plaque index (PI) = 25% and bleeding on probing index (IBP) = 20%)

Exclusion criteria

Exclusion criteria: Patients should not have systemic conditions that could interfere with post-surgical repair, such as diabetes; they should not use medications that affect the gums and/or oral mucosa (phenytoin and other antiepileptic agents; cyclosporine; calcium channel blocking agents); they could not be smokers; pregnant or breastfeeding patients; patients who had a history of allergy to any of the components to be used in the present study

Design outcomes

Primary

MeasureTime frame
It is expected to clinically evaluate patients by checking the probing depth using a millimeter periodontal probe North Carolina

Secondary

MeasureTime frame
It is expected to count the averages of 40 bacterial species present through analysis of subgingival biofilm samples;It is expected to clinically evaluate patients by checking the clinical level of attachment using a millimeter periodontal probe North Carolina

Countries

Brazil

Contacts

Public ContactLaura Gonçalves

Universidade de São Paulo

laurasg@usp.br+55 (14) 996746471

Outcome results

None listed

Source: REBEC (via WHO ICTRP)