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Effectiveness of topical use of flouride and toothbrushing in the control of white spot carious lesions.

Effect evaluation "in vivo" of the fluoride ion and toothbrushing on White spot enamel lesions.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-4752n8
Enrollment
Unknown
Registered
2016-09-26
Start date
2010-04-12
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Demineralization

Interventions

FIRST PERIOD The present study was divided into seven periods. In the first of these, 32 patients who needed their four first premolars extracted were intentionally selected. These participants receiv
32 Brushing with toothpaste without fluoride with the site cariogenic
03 times a day. TOOTH B 32 teeth
Brushing with toothpaste without fluoride with the site cariogenic- 28 days
07 days without being influenced by brushing with toothpaste without fluoride
03 times a day. TOOTH C 32 teeth
07 days without cariogenic site being influenced by brushing with fluoride toothpaste
03 times a day. TOOTH D 32 teeth
Brushing with toothpaste without fluoride with the site cariogenic - 28 days
07 days cariogenic site without being influenced by brushing with toothpaste with fluoride (sodium fluoride 1450 ppm fluoride) - 03 times a day and rinse with mouthwash fluoride (sodium fluoride (NaF)
Other
E06.761.726.794

Sponsors

UFRN - Universidade Federal Do Rio Grande do Norte
Lead Sponsor
UFRN - Universidade Federal Do Rio Grande do Norte
Collaborator

Eligibility

Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; between 12 and 18 years old; who needed as part of the orthodontic treatment of extraction of the first two upper premolars and first two lower premolars; they were healthy and without damage to the labial surface; who were not participating in a preventive program involving the use of fluoride.

Exclusion criteria

Exclusion criteria: Volunteers who were not wearing orthodontic braces; Volunteers using fluoridated products.

Design outcomes

Primary

MeasureTime frame
Enamel demineralization cariogenic challenge after 28 days , as determined by clinical examination using ICDAS II content and Laser Fluorescence DIAGNOdent® , at least 40 % of the teeth, measured at the beginning and end of the cariogenic challenge. ;At the end of 28 days , all specimens received cariogenic site showed enamel demineralization, that is, developed white lesions of enamel, a significant difference ( p < 0.001) between the values ??of clinical examination using ICDAS II index and Fluorescence Laser DIAGNOdent® , baseline and 28 days after the cariogenic challenge.

Secondary

MeasureTime frame
Comparison of the effectiveness of different materials in the clinical treatment of permanent teeth with white lesions enamel ( demineralization ) resulting from biofilm accumulation during orthodontic treatment . To evaluate the materials will be used: toothpaste without fluoride, toothpaste with fluoride ( Sodium Fluoride 1450 ppm fluoride ) and fluoridated mouthwash ( Sodium Fluoride ( NaF) to 0.05 %) in the period of 07 days . And for finding the expected outcomes , it is considered a variation of at least 5 % in the assessment , as measured in the beginning and end of the 07 days , through clinical examination using ICDAS II index and Laser Fluorescence DIAGNOdent® for what differences are considered statistically significant .;In our study, there was no siginificative drop-out (Only 6%).

Countries

Brazil

Contacts

Public ContactCícero Filho

UFRN - Universidade Federal Do Rio Grande do Norte

ciceroflorencio@msn.com+55 (84) 32113105

Outcome results

None listed

Source: REBEC (via WHO ICTRP)