Respiration, Artificial
Conditions
Interventions
It is a randomized controlled clinical trial, triple blind. Randomization was performed using the randomizer.org app. The intervention consisted of daily interruption of sedation and continuous analge
Sponsors
Complexo Hospital de Clínicas Universidade Federal do Paraná
Hospital Universitário Evangélico Mackenzie
Eligibility
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: Children between zero and eighteen years old; admitted to the pediatric intensive care unit; invasive mechanical ventilation; use of continuous sedative and analgesic medications for at least two days; guardian signs the free and informed consent form
Exclusion criteria
Exclusion criteria: Patients diagnosed with intracranial hypertension; Patients who require neuromuscular blocker for more than two days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of mechanical ventilation (days). The first day of intubation was considered and the last day was considered the day of extubation. Extubation failure was considered when below 48 hours and the total mechanical ventilation time count was maintained. It is expected to find a shorter time on mechanical ventilation in the intervention group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Observe the rates of unscheduled extubations;To evaluate the length of stay in the Intensive Care Unit;To observe the presence of alterations in sedation and abstinence scores between the groups. It is expected to find less abstinence in the intervention group. | — |
Countries
Brazil
Contacts
Public ContactMariana Pechebea
Complexo Hospital de Clínicas Universidade Federal do Paraná
Outcome results
None listed