Osteoarthritis, Knee
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Perform at least 300 minutes of physical activity per week. Be between 18 and 59 years old. Both sexes. Be free from functional limitations that prevent the tests and/or the proposed protocol from being performed.
Exclusion criteria
Exclusion criteria: Consuming caffeine-based ergogenic aids. Reporting any type of acute dizziness. Presenting abnormal fluid accumulation (edema), especially in the lower limbs. Presenting impairments in the basilar artery that make cervical manipulations impossible. Diagnoses that affect postural control, such as vestibular dysfunction, Alzheimer's disease, Parkinson's disease, or motor neuron disorders. History of lower limb trauma in the last year. Presence of severe cardiopulmonary disease. Participants currently involved in a structured exercise program focused on postural control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| An increase in lower limb muscle strength is expected, as assessed by the 1RM test, evidenced by a variation of at least 5% between pre- and post-intervention measurements.;A reduction in iR-R intervals and regulation of the sympathovagal balance are expected, as assessed by heart rate variability analysis, evidenced by a variation of at least 5% between pre- and post-intervention measurements.;A reduction in blood pressure is expected, as assessed by oscillometric analysis, evidenced by a variation of at least 5% between pre- and post-intervention measurements;;A reduction in blood inflammatory levels is expected, as assessed by blood analysis of IL-6, TNF-a, and C-reactive protein, evidenced by a variation of at least 5% between pre- and post-intervention measurements.;A reduction in muscle stress levels is expected, as assessed by blood analysis of CK and lactate, evidenced by a variation of at least 5% between pre- and post-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
Brazil
Contacts
Centro Universitário Augusto Motta