Renal Insufficiency, Chronic
Conditions
Interventions
This is a two-arm, double-blind, randomized controlled clinical study. Twenty-four patients with a history of chronic kidney disease on hemodialysis will be divided into two groups: resistance exercis
Sponsors
Universidade do Vale do Rio dos Sinos
Universidade do Vale do Rio dos Sinos
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years of age; both sexes; undergoing conventional dialysis treatment for more than 3 months with a weekly frequency of 3 times a week; with a urea reduction rate greater than 65% or Kt/V greater than or equal to 1.2; who have the conditions to carry out physical tests; and who accept to participate in the training protocol
Exclusion criteria
Exclusion criteria: Patients with cognitive or visual impairment; unstable angina; decompensated congestive heart failure; severe cardiac arrhythmias; pacemaker; uncontrolled arterial hypertension (systolic blood pressure greater than 200 mmHg and diastolic blood pressure greater than 100 mmHg at baseline); decompensated blood glucose (greater than 300 mg/dL); peripheral vascular disease in the lower limbs (such as deep vein thrombosis); disabling neurological sequelae; acute systemic infections; patients with orthopedic problems that prevent their participation; intolerance to electrical current or the electrode; and physically active patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess functional capacity through the distance covered in the six-minute walk test. An increase in the distance covered after the training period of at least 30 m is expected. This data is reported in the literature as the minimum significant difference for the outcome studied. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess lower limb muscle strength by calculating the number of repetitions in the 30-second sit-to-stand test. A 10% increase in the number of repetitions is expected after the training period. The outcome studied is related to autonomy, adverse events such as falls, and functionality in the population of patients with kidney disease on hemodialysis.;To assess quality of life using a specific questionnaire for patients with chronic kidney disease called the Kidney Disease Quality of Life Short Form (KDQOL-SF). An improvement in scores is expected in the domains related to functional and social aspects, since improved functionality leads to improvements in other aspects of the patient's life. It is important to emphasize that quality of life is a predictor of adverse events in the population of patients with chronic kidney disease on hemodialysis.;To assess cognitive function using the Mini-Mental State Examination (MMSE). An improvement or even maintenance of the score is expected, since studies indicate the preservation of neurotrophic factors in participants in physical exercise groups. Furthermore, the possibility of socialization of patients and care throughout the training period by the research team, in addition to changes in lifestyle, is also considered. | — |
Countries
Brazil
Contacts
Public ContactThiago Dipp
Universidade do Vale do Rio dos Sinos
Outcome results
None listed