Chikungunya fever
Conditions
Interventions
It will be recruited 40 patients and subjects will be randomize in two groups of 20 patients each (active group and sham group). A total of 10 sessions lasting 20 minutes each will be administered to
E02.331.750
Sponsors
Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande do Norte
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Man or woman aged 18 or older; be in chronic phase of chikungunya fever least 3 month of the initial infection and show laboratory tests or clinical diagnostic confirmation of chikungunya virus; pain related with more than 4 in a numeric rating scale; to have physical capacity to do physical evaluation and be capable of consenting to treatment and understanding study explanations and questionnaires; having provided informed consent
Exclusion criteria
Exclusion criteria: Electrical implants in the body; a history of epilepsy; people who are clinically contraindicated to receive transcranial direct current stimulation such as having metal embedded in their scalp or brain; psychiatric illness, and history of drug abuse; pregnant women; signs of severity and indication of hospitalization; presence of previous rheumatic disease including gout, rheumatoid arthritis, fibromyalgia, lupus and others chronic pain syndromes with diagnosis prior to chikungunya
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain improvement in patients in the active group who received a 10 day treatment with transcranial direct current stimulation by assessing the visual analog pain scale with a predicted improvement of 3 points for clinically perceptible outcomes | — |
Secondary
| Measure | Time frame |
|---|---|
| Functionality improvement in patients in the active group who received 10 days of treatment with transcranial direct current stimulation assessing the health assessment questionnaire scale with a significant increase in their score;An improvement of 30% of pressure pain threshold and tolerance assessed using algometry in patients in the active group who received 10 days of treatment with transcranial direct current stimulation ;An improvement of 15% of grip strength assessed using hydraulic dynamometer in patients in the active group who received 10 days of treatment with transcranial direct current stimulation ;A moderate improvement in quality of life assessed using short form health survey in patients in the active group who received 10 days of treatment with transcranial direct current stimulation ;A moderate improvement of 30% in severity and effect of pain in daily living activities assessed using brief pain inventory in patients in the active group who received 10 days of treatment with transcranial direct current stimulation | — |
Countries
Brazil
Contacts
Public ContactRodrigo Freitas
Universidade Federal do Rio Grande do Norte
Outcome results
None listed