Periodontitis
Conditions
Interventions
This is a crosssectional and observational clinical study, with quantitative analysis of data, with clinical and laboratory basis, aiming to analyze the mechanisms by which inflammation caused by peri
V03.175.500
Sponsors
Centro de Ciências Biológicas e da Saúde CCBS - UNIOESTE
Centro de Ciências Biológicas e da Saúde CCBS - UNIOESTE
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals over 18 years of age; both genders; admitted to the General ICU of Hospital Universitário do Oeste do Paraná; patients on mechanical ventilation for the first 72 hours; with at least six teeth
Exclusion criteria
Exclusion criteria: Patients with severe maxillofacial trauma that made examination difficult; using complete dentures (upper and lower); pregnant women; immunosuppressed; using any anti-inflammatory and antibiotic for more than three days; serious medical or surgical complications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: It is expected to evaluate that oxidative stress resulting from periodontitis can facilitate the development of pneumonia associated with mechanical ventilation. Verified by analysis of antioxidant system enzymes and oxidative stress.;Outcome found 1: It was observed that the increase in oxidative stress, caused by periodontitis, led to an imbalance in the antioxidant status, facilitating the development of pneumonia associated with mechanical ventilation. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome is expected. | — |
Countries
Brazil
Contacts
Public ContactBruna Silva
Centro de Ciências Biológicas e da Saúde CCBS - UNIOESTE
Outcome results
None listed