HIV
Conditions
Interventions
This is an observational, cross-sectional study nested within a cohort, to be conducted in Maceió, AL, with a representative sample (n = 583) of people living with HIV under clinical follow-up at thre
aerobic fitness (via the modified Canadian Aerobic Fitness Test or the 2-minute step test)
muscular fitness (via handgrip strength, arm curl test, chair stand test, and the Short Physical Performance Battery)
body fat and arm muscle area (via anthropometry)
muscle mass (via ultrasound)
phase angle (via bioelectrical impedance)
blood pressure (via automatic oscillometric device)
total cholesterol, fractions, and triglycerides (via lipid profile)
blood glucose
C-reactive protein, interleukin-6, and tumor necrosis factor-alpha
as well as carotid intima-media thickness and the presence of atherosclerotic plaque (via ultrasound).
Sponsors
Universidade Federal de Alagoas
Universidade Federal de Alagoas
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 18 years or older; both sexes; diagnosis of HIV infection; outpatient care at Posto de Assistência Médica (PAM) Salgadinho, Hospital Escola Dr. Helvio Auto (HEHA), and Hospital Universitário Professor Alberto Antunes (HUPAA); availability of clinical and laboratory records; and regular use of Antiretroviral Therapy for at least six months
Exclusion criteria
Exclusion criteria: Presence of neurological disorders that affect the motor system; inability to stand and/or walk; psychiatric disorders that prevent completion of the questionnaires; speech and/or hearing impairments; diagnosis of type 1 diabetes mellitus; genetically originated metabolic diseases; transgender individuals; cancer; pregnant or postpartum women; contraindications to physical activity that prevent them from completing the questionnaires (excludes them only from the aerobic test); people experiencing homelessness or deprived of liberty; amputee patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the phase angle and cardiovascular risk factors (lipid-glycemic-inflammatory, vascular, and metabolomic profiles) in People Living with Human Immunodeficiency Virus, verified using bioelectrical impedance, blood laboratory analysis, ultrasound, and blood pressure measurements, based on the observation of raw phase angle values in degrees, serum biomarker concentrations, carotid intima-media thickness in millimeters, and blood pressure values in millimeters of mercury | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess phase angle, physical activity, sedentary behavior, aerobic fitness, muscular fitness, and body composition (body fat and muscle mass), verified using bioelectrical impedance, the International Physical Activity Questionnaire, accelerometry, motor performance tests, and anthropometry, based on the observation of raw phase angle values in degrees, movement volume in minutes, strength indices in kilograms, and body measurements in percentages and centimeters | — |
Countries
BR
Contacts
Public ContactLuiz Rodrigo Lima
Universidade Federal de Alagoas
Outcome results
None listed