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The effect of topical anesthesia on patients with dental anxiety

The comparative effect of topical anesthesia on patients with different levels of dental anxiety

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-459d4r
Enrollment
Unknown
Registered
2019-10-29
Start date
2018-09-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental anxiety

Interventions

Topical anesthesia with 20% benzocaine (20 subjects)
Topical anesthesia with the combination of lidocaine (25 mg/g) and prilocaine (25mg/g) (20 subjects)
Control: Ointment without an active ingredient (placebo) (20 subjects)
The application of topical medications will be followed by anesthetic injection of the major palatal nerve with 2% lidocaine hydrochloride associated with 1: 100,000 norepinephrine (all the subjects).
Drug

Sponsors

Faculdade de Odontologia da Universidade de São Paulo
Lead Sponsor
Faculdade de Odontologia da Universidade de São Paulo
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA I Need for extraction of bilateral superior third molars.

Exclusion criteria

Exclusion criteria: Patients with systemic comorbidities; Pregnant or breastfeeding women; Patients taking continous use medications; Patients with a history of anemia or methemoglobinemia;  Patients with a history of drug allergy to the drugs selected for the study.

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of anxiety on pain perception after topical anesthesia immediately after the injection, using quantitative (hemodynamic variations) and qualitative (verbal pain scale) methods. The significance level among groups will be set as 5%.

Secondary

MeasureTime frame
To evaluate whether topical anesthesia has a physiological or a psychological effect on pain perception in dental anxiety patients, using quantitative (hemodynamic variations) and qualitative (verbal pain scale) methods. The significance level among groups will be set as 5%.

Countries

Brazil

Contacts

Public ContactEmanuela Ferraz

Faculdade de Odontologia da Universidade de São Paulo

emanuelaferraz@usp.br+55(11) 2648-8038

Outcome results

None listed

Source: REBEC (via WHO ICTRP)