Chronic Renal Failure.
Conditions
Interventions
Evaluations will be performed before and after the dialysis treatment, the intervention occurs in the first 2 hours of hemodialysis during 24 sessions, the variables analyzed: respiratory muscle stren
Other
E02.779
Sponsors
Universidade Federal de Alfenas UNIFAL-MG
Hospital Casa de Caridade Alfenas Nossa Senhora do Perpétuo Socorro
Eligibility
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: both genders; individuals within the age group 20 to 70 years; patients from the Hospital Casa de Caridade Alfenas Nossa Senhora do Perpétuo Socorro, Hemodialysis (HD) sector, submitted to HD three times a week.
Exclusion criteria
Exclusion criteria: Exclusion criteria: hemodynamic instability; pathological fractures; cognitive deficit or incoordination to run the apparatus used; Diabetes Mellitus and Systemic Arterial Hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1- Improvement of 20% of respiratory and peripheral function after 24 intervention sessions. Through evaluation of the Peak of Respiratory Flow, Peak Flow of Cough, through Peak Flow, this evaluation occurs every day before and after the intervention.;Expected outcome 2- Improvement of 20% respiratory and peripheral muscle strength after 24 intervention sessions. Through monovacuometry to see inspiratory and expiratory muscle strength, Upper limb dynamometry to see manual grip strength, modified sphygmomanometer test to observe lower limb strength, muscle strength graduation from the Medical Research Council (MRC), to see muscle strength through evaluation, this evaluation occurs every day before and after the intervention.;Expected Outcome 3- Improved 10% of the biomarkers through laboratory tests performed by monthly collections of pre and post urea, creatinine, calcium, ionic calcium, phosphorus, potassium, TGP, glycemia, HBSAG, ANTI-HCV, arterial blood gases, albumin , hematocrit, hemoglobin, platelets, leukocytes, bilirubin; and quarterly collections of pre and post urea, creatinine, calcium, phosphorus, potassium, TGP, glycemia, HBSAG, ANTI-HCV, ANTI HBS, protein, serum iron, phosphatase, transferrin saturation, ferritin, arterial blood gas, ionic calcium, PTH , globulin, hematocrit, hemoglobin, platelets, leukocytes, bilirubin. All these values will be obtained by the routine exams performed in the Hemodialysis Sector. Tests performed once a month by the hemodialysis team. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1 - Improvement of 15% of the organic function through the Sequential Organ Failure Assessment (SOFA), evaluating the variables of the Respiratory System (PaO2 / FiO2), Coagulation (Platelets), Cardiovascular (Hypotension), Fig (bilirubin), Nervous System Central (Glasgow Coma Scale), Renal (creatinine), seen through laboratory tests, exams are collected once a month by the hemodialysis team.;Expected outcome 2 - 15% Improvement in Quality of Life after 24 sessions, using the Kidney Disease Quality of Life Short Form (KDQOL-SF) quality of life questionnaire. These tests are applied before beginning treatment and after the 8 weeks of treatment. | — |
Countries
Brazil
Contacts
Public ContactFernanda Oliveira
Universidade Federal de Alfenas UNIFAL-MG
Outcome results
None listed