inflammation
Conditions
Interventions
Group 1 (case) consisted of patients admitted to the COVID-19 ICU ward with the confirmed diagnosis for COVID-19 (PCR test n=23). Group 2 (control n=11) was made up of patients admitted to the general
Sponsors
Universidade Estadual do Oeste do Paraná
Hospital Universitário do Oeste do Paraná - HUOP
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Individuals, aged 18 to 70 years, with respiratory failure treated at the COVID 19 Ward and at the ICU of the University Hospital of West Paraná HUOP/UNIOESTE, in Cascavel/Pr
Exclusion criteria
Exclusion criteria: Wearers of complete upper and lower dentures simultaneously; Smokers; Pregnant women; Ethyls; Users of any type of drug; who are taking antidepressants, anti-inflammatory drugs, anticonvulsants, calcium blockers, or any other drug that may interfere with the results of this study; Under 18s
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1. It is expected to find a greater effect of periodontal inflammation on gingival crevicular fluid in patients with COVID-19.;Endpoint found 1 was observed a reduction in the periodontal inflammatory profile of patients with COVID-19. Considering that the sample studied was small, it is suggested that dexamethasone therapy in the group of patients with COVID-19 may have led to the suppression of periodontal inflammation. | — |
Secondary
| Measure | Time frame |
|---|---|
| dexamethasone in the COVID-19 patient group, may have led to suppression of periodontal inflammation. | — |
Countries
Brazil
Contacts
Public ContactPatricia Nassar
Universidade Estadual do Oeste do Paraná
Outcome results
None listed