Periodontal Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Presence of at least 15 natural teeth, excluding third molars and teeth indicated for extraction; diagnosis of generalized stage III grade A and B periodontitis, with at least 30% of the teeth with at least one site with probing depth and clinical level of insertion greater than or equal to 5 mm and bleeding on probing.
Exclusion criteria
Exclusion criteria: Presence of other systemic conditions which can affect the progression of periodontitis or the response to its treatment; long-term administration of anti-inflammatory or immunosuppressive medication; periodontal treatment and / or use of antimicrobials in the last 6 months; use of probiotics in the last 6 months; continuous use of mouthwashes containing antimicrobial agents in the last 6 months; need for prophylactic antibiotic therapy for routine dental procedures; extensive prosthetic rehabilitation; tobacco consumption in the last 5 years; pregnancy and lactation and gastrointestinal diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome: Reduction in loss of clinical insertion level; assessed by measuring the clinical level of insertion in millimeters, which corresponds to the distance between the cemento-enamel junction and the bottom of the periodontal pocket; considering a variation of at least 15% in the data collected at the beginning and at the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Reduction in drilling depth; measured in millimeters from the gingival margin to the bottom of the periodontal pocket; at the beginning and end of the study. | — |
Countries
Brazil
Contacts
Universidade de São Paulo