Improvement of skin quality, improvement of scar tissue
Conditions
Interventions
Select 10 patients with indication of abdominoplasty and who have cesarean scar, harvest 20ml of fat from the abdomen through liposuction, infiltrate this fat on only one side of the cesarean scar. A
Procedure/surgery
G12.875.545.340
Sponsors
Universidade Federal de Pernambuco - UFPE
Universidade Federal de Pernambuco - UFPE
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Women; abdominoplasty indication; between 20 and 50 years; BMI below 30; previous cesarean scar.
Exclusion criteria
Exclusion criteria: Smokers; patients with systemic disease; use of any medication for chronic use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The two pieces: the previously fat grafted area in the right hemisphere and, analogously, a control area on the other side, that is: another 3 x 3 cm square contralateral sample including the last 3 cm of the cesarean scar will go to analysis in the Pathology Sector of the HC-UFPE where the possible qualitative and quantitative changes of the lipoenxert dermis will be evaluated in relation to the dermis that was not lipografted. By checking whether or not there are changes in the skin of an area that has received fat grafting, attest to whether or not there is changes in the scar tissue that received a fat graft and, if so, to identify what changes have occurred.;Ten patients had a mean age of 35.9 years (standard deviation of 10.1 years) and mean BMI of 24.1 kg / m2 (standard deviation of 3.1 kg / m2). Two surgical specimens were obtained from each patient. Randomly, one specimen was grafted and the other not, resulting in 10 samples from each group. From the samples where the graft was grafted, it was verified the presence of viable grafted adipocytes in all of them. Thus, 50% of the study samples showed signs of successful fat grafting. As for the dermis thickness, it was verified that both the samples that received fat grafting and those that did not received had a high prevalence of a mild inflammatory process (70.0% and 90.0%, respectively). Furthermore, the homogeneity test was not significant (p-value = 0.582), indicating that there was no difference in the inflammatory process between the group of samples that received and did not receive the fat graft. As for the dermis thickness, a higher mean was observed in the group of samples that did not receive fat grafting (mean = 2.27 mm) compared to the fat gratfed group (mean = 2.26 mm). Although the difference was not significant (p-value = 0.973), indicating that the fat graft treatment did not significantly alter the dermis thickness. In relation to the density of vascularization, there was a higher mean in t | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactJuan Maricevich
Universidade Federal de Pernambuco - UFPE
Outcome results
None listed