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Ability to spontaneous breathing test to identify successful withdrawal of the tube and mechanical ventilator in preterm infants

Evaluation of the Spontaneous Breathing Test (TRE) as a predictor of successful extubation of mechanical ventilation in preterm newborns

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-43rsyw8
Enrollment
Unknown
Registered
2021-05-12
Start date
2017-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary dysplasia originating in the perinatal period

Interventions

Experimental group (n=33): Firstly, endotracheal aspiration will be performed between 30 minutes and one hour before TRE application. After the time, the newborn will be placed in dorsal decubitus wit

Sponsors

Hospital Sofia Feldman/ Fundação de Assistencial Integral à Saúde
Lead Sponsor
Hospital Sofia Feldman/ Fundação de Assistencial Integral à Saúde
Collaborator

Eligibility

Age
No minimum to 37 Weeks

Inclusion criteria

Inclusion criteria: NB of gestational age minor than 37 weeks; Signature of the free and informed consent term (EHIC) by the mother or responsible for the NB; Conduct present respiratory; First extubation; Respiratory frame stable for at least 6 hours; Supporting ventilatory parameters: Respiratory rate (RR) 15 to 28 hours / Inspiratory peak pressure minor or equal than 16 cmH2O / Positive expiratory pressure minor or equal than 5 cmH2O / FiO2 minor or equal than0.35 / PH 7,25-7,45 (PaO2) 50-80 mmHg / Carbon dioxide arterial pressure (PaCO2) minor than 40 mmHg / Mean airway pressure minor or equal than 8 cmH2O

Exclusion criteria

Exclusion criteria: Presence of severe heart disease, malformation, genetic syndrome and neuromuscular disease; Presence of audible air leakage around the endotracheal tube; Continuous sedation; Hemodynamically unstable.

Design outcomes

Primary

MeasureTime frame
Success in SBT being able to predict success in extubation. Fisher's Exact Test was applied to verify the association between extubation outcome between groups.

Secondary

MeasureTime frame
Hemodynamic and respiratory stability assessed during the test and after extubation through the variables heart and respiratory rate, systolic blood pressure, peripheral oxygen saturation, exertion and respiratory pattern

Countries

Brazil

Contacts

Public ContactSimone Ribeiro

Hospital Sofia Feldman

simonensribeiro@gmail.com5531986232400

Outcome results

None listed

Source: REBEC (via WHO ICTRP)