Evaluation of Medicines
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients will be included: over 18 years old; who have not been transferred from the ICU to other hospitals; with an APACHE II score 20; with no current cancer diagnosis; absence of surgery in the last six months; and, who presented at least one PRM identified by the research pharmacists through the DAM medical record
Exclusion criteria
Exclusion criteria: We will exclude patients: with data collection beginning after the first 48 hours of hospitalization; with hospital stay less than 72 hours; who are admitted for palliative care; higher probability of early death (defined as death occurring between the 48th and 72nd hours of ICU admission); diagnosed with suspected or confirmed brain death; aware that they refuse to participate in either group after randomization; who refuse to participate in the study after recovering an adequate state of consciousness for decision-making, when their entry is made by the authorization of family members and / or guardian.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In this study, the primary outcome was the length of stay in the ICU (in days). A shorter hospital stay was observed in the intervention group so that the intervention group had an average of 7 days, while in the control group an average of 10.7 days was observed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes were the Sequential Organ Failure Assessment (SOFA) and death scores. In all measures, improvements were observed in the intervention group, reduction in the SOFA score during hospitalization and reduction in the death rate | — |
Countries
Brazil
Contacts
Universidade Federal de Sergipe;Universidade Federal de Sergipe