Malignant neoplasm of thyroid gland
Conditions
Interventions
The study will be conducted in five groups of participants. For benign nodules (Classification II), one group of 20 participants will undergo microwave ablation guided by ultrasonography, performed in
G01.358.500.505.810.500
Sponsors
Instituto do Câncer Arnaldo Vieira de Carvalho
Instituto do Câncer Arnaldo Vieira de Carvalho
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Benign Nodule Arm Participants older than 18 years treated at Instituto do Câncer Arnaldo Vieira de Carvalho; patients with benign nodules classified as II by fine-needle aspiration biopsy (FNAB); nodules with a diameter greater than or equal to 3 cm; nodules with a diameter greater than or equal to 2 cm associated with compressive or aesthetic symptoms with surgical indication; participants who agree to participate in the study and sign the informed consent form (ICF); patients with at least 16 months of clinical follow-up after the start of treatment Malignant Nodule Arm Participants older than 18 years treated at Instituto do Câncer Arnaldo Vieira de Carvalho; patients with malignant nodules classified as V or VI by fine-needle aspiration biopsy (FNAB), i.e., suspicious for or consistent with papillary carcinoma; nodules with a diameter less than or equal to 1 cm with surgical indication; participants who agree to participate in the study and sign the informed consent form (ICF); patients with at least 16 months of clinical follow-up after the start of treatment
Exclusion criteria
Exclusion criteria: Benign Nodule Arm and Malignant Nodule Arm Participants diagnosed with hyperthyroidism; participants without cognitive ability to understand the informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to demonstrate the efficacy and safety of radio frequency ablation with microwave ablation in relation to the reduction rate of benign thyroid nodules through the use of ultrasound in up to 16 months of follow-up.;It is expected to demonstrate the oncological feasibility, efficacy, safety and costs of radio frequency ablation, microwave ablation compared to conventional surgery in papillary carcinomas = 1 cm through follow-up of up to 16 months | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected | — |
Countries
Brazil
Contacts
Public ContactRafael De Cicco
Instituto do Câncer Arnaldo Vieira de Carvalho
Outcome results
None listed