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Effects of the inclusion of a Functional Circuit to Aerobic and Resistance Training on functionality, physical activity in daily life and inflammation of patients with Chronic Obstructive Pulmonary Disease

Effects of the inclusion of a Functional Circuit to Aerobic and Resistance Training on functionality, physical activity in daily life and immuno-metabolic response of patients with Chronic obstructive pulmonary disease (COPD): a randomized clinical trial with follow up

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3zmh3r
Enrollment
Unknown
Registered
2018-05-04
Start date
2018-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstrutive pulmonary disease

Interventions

Patients with COPD will be randomized to an 8-week training program with 3 weekly sessions, including resistance training, aerobic and functional circuit (FTG) or conventional (resisted and aerobic) (
and simple pulley equipment (Ipiranga® - Brazil) for upper limbs. The training intensity will be 60 to 80% of the test of a maximum repetition (1RM) performed previously, with 3 sets of 10 repetitions
however, when this is less than 4, there will be a 5% increase in training intensity until the weeks of aerobic training are completed. FTG will also perform functional circuit training as follows: Th
Other
E02.760.169.063.500.387

Sponsors

Universidade Estadual Julio de Mesquita Filho - UNESP
Lead Sponsor
Ercy Mara Souza Ramos
Collaborator

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: patients diagnosed with COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD); clinically stable patients without exacerbations or changes in medications for at least 30 days; they are not smokers; patients who do not undergo home oxygen therapy; patients without pathological conditions that prevent physical activity; no severe or unstable heart disease diagnosed by electrocardiogram; does not present any other pathological condition that may influence the systemic inflammatory process; not participating in another systematic exercise program.

Exclusion criteria

Exclusion criteria: Exacerbations or intercurrences that prevent the continuity of the training protocol; frequency of less than 75% of the sessions.

Design outcomes

Primary

MeasureTime frame
It is expected that the proposal to insert a functional circuit to the proposed exercise programs in pulmonary rehabilitation will present positive results on functionality (functional capacity, muscular strength, balance), body composition, heart rate variability,peripheral muscle oxygenation, aerobic capacity and recovery after maximum effort, dyspnea, quality of life, daily life activities and increased physical activity in the daily life of patients with chronic obstructive pulmonary disease (COPD); it is expected to be able to elucidate the complex molecular immuno-metabolic process that occurs in the disease and that is not yet fully elucidated. It is expected that the proposed training will promote beneficial changes in the immune metabolic profile in order to increase the synthesis of anti-inflammatory cytokines and, in return, reduce the inflammatory process that occurs in the disease. Is expected that the training to present good acceptability and satisfaction for patients with COPD.

Secondary

MeasureTime frame
It is expected that the possible increase in physical activity in daily life and functionality be maintained after three months of the end of the training.

Countries

Brazil

Contacts

Public ContactErcy;Fabiano Ramos;Lima

Universidade Estadual Julio de Mesquita Filho - UNESP ;Universidade Estadual Julio de Mesquita Filho - UNESP

ercy@fct.unesp.br;fabiano_ffl@hotmail.com55 (18) 32295821;55 (18) 32295821

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 20, 2026