Diabetes Mellitus
Conditions
Interventions
Test group: Initially, 25 patients will be submitted to anamnesis, will receive prophylaxis and / or supragingival scraping ("cleaning" on all teeth) and instruction on oral hygiene. After 7 days, pat
Procedure/surgery
Dietary supplement
Other
E06.721.189.350
G07.203.300.456.500
Sponsors
Universidade de São Paulo
Universidade de São Paulo
Eligibility
Inclusion criteria
Inclusion criteria: Presence of at least 15 natural teeth, excluding third molars and teeth indicated for extraction; diagnosis of generalized stage III grade C periodontitis, with more than 30% of the sites with probing depth and clinical level of insertion greater than or equal to 4 mm and bleeding on probing of at least 30% of the teeth; presence of type II diabetes mellitus diagnosed at least 5 years ago, with glycated hemoglobin levels between 7% and 11%, treatment with diet and supplementation with insulin or hypoglycemic agents; presence of a good state of general health with the exception of diabetes mellitus.
Exclusion criteria
Exclusion criteria: Presence of other systemic conditions, with the exception of diabetes mellitus, which can affect the progression of periodontitis or the response to its treatment; long-term administration of anti-inflammatory or immunosuppressive medication; periodontal treatment and / or use of antimicrobials in the last 6 months; use of probiotics in the last 6 months; continuous use of mouthwashes containing antimicrobial agents in the last 6 months; need for prophylactic antibiotic therapy for routine dental procedures; extensive prosthetic rehabilitation; tobacco consumption in the last 5 years; pregnancy and lactation; diabetic complications, such as nephropathy, neuropathy, and peripheral cardiovascular and vascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome: Reduction in loss of clinical insertion level; assessed by measuring the clinical level of insertion in millimeters, which corresponds to the distance between the cemento-enamel junction and the bottom of the periodontal pocket; considering a variation of at least 15% in the data collected at the beginning and at the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Reduction in drilling depth; measured in millimeters from the gingival margin to the bottom of the periodontal pocket; at the beginning and end of the study.;Expected outcome 2: Reduction in bleeding on probing; assessed dichotomously at 6 sites per tooth; at the beginning and end of the study.;Expected outcome 3: Reduction in glycated hemoglobin levels; assessed through blood analysis; at the beginning and end of the study. | — |
Countries
Brazil
Contacts
Public ContactFlávia Furlaneto
Universidade de São Paulo
Outcome results
None listed