Amyotrophic lateral sclerosis, pulmonary capacity, cough
Conditions
Interventions
A conventional Respiratory Care Group (CC): Guidance and training for caregivers regarding prevention of bronchoaspiration, bed positions, stimulation of mobilization, elimination of secretions with c
upper airway aspiration
elimination of assisted cough secretions using manual or mechanical insufflation
guidance to caregivers regarding prevention of bronchoaspiration, bed positions, stimulation of mobilization, secretion elimination and assisted cough.
Each group will have 22 participants, totaling
G12.2
E02.760.169.063.500
Sponsors
Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande do Norte
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the study were patients with ALS, between 18 and 70 years old, with good cognitive level to understand the evaluative tests; patients not restricted to bed; the presence of a responsible caregiver who accepts the training and follows the program; have a telephone to contact the service team.
Exclusion criteria
Exclusion criteria: Will be excluded from the study volunteers who are unable to perform the requested maneuvers correctly or who give up performing them during the execution for evaluation. Patients with cardiac, respiratory, musculoskeletal comorbidities, intellectual comprehension difficulty or dementia evaluated, with any other comorbidity that prevents them from performing the tests or who have difficulty performing the tests; and, smoking patients. Patients residing in regions that do not have rear medical staff in the city or in a nearby urban center; patients residing in regions of high hazard or difficult for physiotherapists to access.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak cough flow in liters/minute by optoelectronic plethysmograph analysis.;Physical function through the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised - ALSFRS-R.;Number of exacerbations (acute) of the patients through urgent and emergency medical assistance. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chest wall kinematics during Cough Assist assisted coughing by optoelectronic plethysmography (BTS Bioengineering, Italy).;The absolute and predicted Forced Vital Capacity (FVC), forced expiratory volume in the 1st second (FEV1) and FEV1/FVC by spirometry.;Respiratory muscle strength through maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), sniff nasal inspiratory pressure (SNIP) and nasal expiratory pressure using the manovacuometer.;Demographic (age and gender), anthropometric assessments (height and weight) and body mass index | — |
Countries
Brazil
Contacts
Public ContactKaren Pondofe
Universidade Federal do Rio Grande do Norte
Outcome results
None listed