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The effect of laser treatment on reducing eye pressure and reducing eye drops in patients with Glaucoma

Selective laser trabeculoplasty as initial therapy in patients with open-angle glaucoma and ocular hypertension. Assessment of effectiveness, safety and economic impact

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3y32sh
Enrollment
Unknown
Registered
2020-09-08
Start date
2020-07-08
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, ocular hypertension

Interventions

The selected patients will undergo a period of medication washout to observe the basal eye pressure by applanation tonometry, which will be the comparator after one year of follow-up. After the washou
Procedure/surgery
E02.594

Sponsors

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Lead Sponsor
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Collaborator

Eligibility

Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: People with open-angle glaucoma or high-risk ocular hypertension; Mild to moderate glaucoma; 40 to 80 years of age; Patient being treated with topical hypotensive eye drops.

Exclusion criteria

Exclusion criteria: Advanced open-angle glaucoma; Glaucoma secondary to trauma and medication; In treatment for other ophthalmic diseases that require laser applications or treatment with intraocular injections; Previous incisional glaucoma surgery; Previous laser treatment for glaucoma; Presence of corneal opacity that prevents adequate vision of the trabecular meshwork; Intraocular inflammation in the last 3 months or previous surgery in the last 6 months

Design outcomes

Primary

MeasureTime frame
Difference in percentage reduction in intraocular pressure after 1 year of selective laser trabeculoplasty. Compared with basal intraocular pressure after washout.

Secondary

MeasureTime frame
Proportion of patients with controlled intraocular pressure and less than 18 mmHg at the end of one year of follow-up;Reduction in the amount of eye drops used at the end of the follow-up

Countries

Brazil

Contacts

Public ContactLeopoldo Barbosa

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

leopoldo.barbosa@icloud.com+55-011-981060626

Outcome results

None listed

Source: REBEC (via WHO ICTRP)