Ocular Hypertension
Conditions
Interventions
100 eyes from 50 patients will be chosen for the administration of eye drops or vaporization according to an Excel pseudorandom number table. For each patient,one eyedrop will be aplied onto one eye
Drug
Device
Sponsors
Universidade Estácio de Sá
Universidade Estácio de Sá
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Adult volunteers; both genders; Consulted at the Policlinica Ronaldo Gazolla ophthalmological clinic; Need to perform aplanation tonometry for intraocular pressure measurement.
Exclusion criteria
Exclusion criteria: Volunteers with corneal disease; Refusal in signing the informed consent; Mentally retarded that does not understand research procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome: esthesiometric corneal measurements with 0,4% oxibuprocaine spray administration in closed eyes, similar to eye drop aplication in open eyes. Esthesiometric measurement will be realized by a Cochet-Bonnet esthesiometer, before, 1, 5, 10 and 15 minutes after oxibuprocaine topical administration in each eye. Esthesiometric similar values are the ones produced by mononylon esthesiometric length equal or inferior to 10 mm between eyes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 6: Eye drop application time will be 10% greater than that of anesthetic vaporization. The outcome will be measured by observing that the average time in seconds needed to vaporize the patients will be at least 10% lower than that for instilling eye drops in the eye.;Expected outcome 7: The examination of tonometry will be performed after anesthetic application in vaporized eyes or where eye drops have been instilled. The outcome will be measured by observing the accomplishment of tonometry test between 1 minute and 5 minutes after the application of anesthetic by spray or drops.;Expected outcome 1: Level of facility perceived by the patient to apply the anesthetic by vaporization will be greater than the application of anesthetic instilled by drops. This parameter will be measured by observing that the mean score to the responses for question 5 will be at least 10% higher than the mean score to the responses for question 4 from the perception form for topical drug administration.;Expected outcome 2: The number of difficulties encountered for drop application will be 10% greater than that found for topical administration by vaporization. The outcome will be measured by the percentage of positive responses to question 6 to be 10% higher than the percentage of positive responses to question 7 from the perception form for topical drug administration;Expected outcome 3: The precision of vaporization will be 10% greater than drop instillation. The outcome will be measured by noting that the percentage of the answers in question 12 will be 10% higher than the percentage of answers in question 8 from the perception form for topical drug administration;Expected outcome 4: Topical administration repetition will be 10% lower for the spray than for eye drop instillation. The outcome will be measured by observing that the percentage of responses from question 9 will be 10% higher than that of question 13 from the perception form for topical drug adminis | — |
Countries
Brazil
Contacts
Public ContactArlindo Portes
Universidade Estácio de Sá
Outcome results
None listed