Muscle Weakness
Conditions
Interventions
This is a randomized, controlled, two-arm, unblinded clinical study. The control group consists of nine hemodialysis patients who will undergo an intradialytic physiotherapy program based on multifunc
s capabilities. Experimental group: nine patients on hemodialysis who will undergo an intradialytic physiotherapy program associated with inspiratory muscle training. This group will undergo the same
Sponsors
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Individuals with chronic renal failure undergoing hemodialysis in the Nephrology Department of the Hospital for at least three months of hemodialysis; of both sexes; between 18 and 70 years old; in stable clinical conditions
Exclusion criteria
Exclusion criteria: Patients who will undergo kidney transplantation during the intervention period; who are unable to understand and follow the research protocols; people in wheelchairs; who have medical contraindications to performing physical and/or breathing exercises; those who do not agree to sign the free and informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: improvement in functional capacity, verified by an increase in the distance covered in the 6-minute walk test after 8 weeks of respiratory muscle training associated with physiotherapy based on functional exercises;Finding outcome 1: no statistically significant improvement in functional capacity was observed. The control group showed an increase in the distance covered in the 6-minute walk test from 360±39.2 meters to 381.9 meters, while the intervention group showed a reduction from 345.3 to 310.8 meters, with no statistically significant difference between the groups (p=0.17) | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: improvement in balance and mobility, verified through the timed up and go test; increased inspiratory muscle strength, verified through the manovacuometry test; and improved quality of life, verified through the Kidney Disease and Quality of Life Short Form instrument after 8 weeks of respiratory muscle training associated with physiotherapy based on functional exercises;Finding outcome 2: there was an improvement in balance and mobility in the control group, evidenced by a reduction in the timed up and go test time, with a statistically significant difference (p=0.04), while the intervention group showed a reduction without statistical significance (p=0.39). Regarding respiratory muscle strength, both maximum inspiratory pressure and maximum expiratory pressure increased in both groups, but without a statistically significant difference. In the control group, maximum inspiratory pressure increased from 69.5 (95% confidence interval: 41–98) to 81 (61–99), with p=0.09, and in the intervention group from 70 (24–115) to 78.7 (34–120), with p=0.06. Maximum expiratory pressure in the control group ranged from 99.5 (57–152) to 104.5 (55–158), with p=0.67, and in the intervention group from 94.4 (51–138) to 104.4 (73–139), with p=0.24. No results regarding quality of life were presented | — |
Countries
BR
Contacts
Public ContactEliane Winkelmann
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Outcome results
None listed