Hemodynamic Phenomena
Conditions
Interventions
The proposal is a prospective, randomized, double-blind study comparing the hemodynamic response to tracheal extubation in 226 patients undergoing placebo infusion (0.9% saline) or metoprolol, all sur
T1: at the end of surgery (reversal of neuromuscular block)
T2: Pre-infusion (one minute before the study drugs are infused)
T3: first minute of the infusion
T4: end of infusion
T5: during extubation
T6: one minute after extubation
T7: three minutes after extubation
T8: five minutes after extubation
T9: ten minutes after extubation
T10: aft
D27.505.519.625.050.200. 200
Sponsors
Hospital de Base do Distrito Federal
Hospital de Base do Distrito Federal
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 60 years, scheduled to undergo surgery under general anesthesia. Physical status 1 2 and 3 of the American Society of Anesthesiology (ASA).
Exclusion criteria
Exclusion criteria: Patients with contraindications or a history of hypersensitivity to the drugs involved in the study. Patients with heart, lung, kidney, liver or neurological disease. Patients who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We hope to find a reduction in the incidence of respiratory complications, such as coughing, bucking, bronchospasm or laryngospasm during tracheal extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| We hope to find a reduction in the incidence of cardiovascular complications, such as tachycardia and hypertension during tracheal extubation. | — |
Countries
Brazil
Contacts
Public ContactFabricio Mendonça
Outcome results
None listed