Chronic Obstructive Pulmonary Disease
Conditions
Interventions
This is a prospective randomized controlled single-blind clinical trial with two groups. Intervention group: 40 patients with chronic obstructive pulmonary disease will receive conventional pulmonary
each block will have 50% of the participants. Each participant will have a number that will be generated by computer. Accessing the website https://www.random.org/sequences/, where the lowest value wi
E02.190
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Sign the informed consent form thus authorizing their participation in the research; participants with a diagnosis of Chronic Obstructive Pulmonary Disease; men or women; age over 45 years; they will need to walk without assistance or supervision from others even if they use some type of walking aid
Exclusion criteria
Exclusion criteria: Hypercalcemia; severe vitamin D deficiency (25-hydroxyvitamin D < 12 nanograms per milliliter); uncompensated thyroid function disorders; creatinine clearance < 45 milliliters per minute; recent history of hip fracture (< 12 months); alcohol or illicit drug dependence; use of teriparatide; calcitonin; androgens; estrogens or selective estrogen receptor modulators in the past 6 months; use of bisphosphonates in the past 12 months; osteoarthritis with synovitis; use of osteoarticular prostheses; severe heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate, in patients with Chronic Obstructive Pulmonary Disease (COPD) undergoing a conventional pulmonary rehabilitation protocol for 12 weeks, the possible additional effects of low-intensity whole-body mechanical vibration on several health parameters, compared to a control group undergoing only the conventional protocol. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigate possible changes in the musculoskeletal system through body composition, neuromuscular function parameters and blood biomarkers of bone and muscle metabolism;Assess possible changes in cardiorespiratory function and biochemical markers of inflammation;To assess changes in bone structure through high-resolution peripheral computed microtomography (HRpQCT) analysis;To examine the effects of vibration on patients' activities of daily living, quality of life and cognitive function;To analyze changes in peripheral blood perfusion of patients induced by the effects of vibration through thermography | — |
Countries
Brazil
Contacts
Public ContactRafael Melo
Universidade Federal de São Paulo
Outcome results
None listed