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Effects of physical activity on cognitive functions (attention, memory, processing speed and executive function), bain-derived neurotrophic factor (BDNF) and cortisol levels in older women.

Effects of physical activity on cognitive function and BDNF and cortisol levels in older women.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3wk3cr
Enrollment
Unknown
Registered
2016-10-17
Start date
2014-05-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive impairment, depression, anxiety

Interventions

Intervention: Physical activity (physical exercise) protocol. Intervention group (n=20): Subjects will participate in a three-month physical activity intervention. Physical activity will be done in
Other
G11.427.590.530.698.277
G11.427.590.530.698.277.968
E02.779.483.750
E02.779.483.875

Sponsors

Pontifícia Universidade Católica do Rio Grande do Sul
Lead Sponsor
Pontifícia Universidade Católica do Rio Grande do Sul
Collaborator

Eligibility

Sex/Gender
Female
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: Ages between 60 and 90 years; not being physically active in the last 6 months; at least 4 years of formal education; present a medical certificate permiting the participation in the physical activity protocol.

Exclusion criteria

Exclusion criteria: Previous or current history of neurological diseases; dementia; major unstable medical conditions; pathological conditions that modify cortisol and BDNF levels; visual and hearing dysfunctions; use of medications that interfere with cognitive functions, BDNF levels or HPA axis; previous or current drug abuse; lower-limb amputation or bone fractures in the past 6 months.

Design outcomes

Primary

MeasureTime frame
Expected Outcome Contextual memory improvement, evaluated by the performance (number of correct responses) on the contextual memory task, considering an increase of at least 5% from the pre to post intervention condition.;Observed Outcome Contextual memory improvement, evaluated by the performance (number of correct responses) on the contextual memory task, of more than 5% from the pre to post intervention condition.—

Secondary

MeasureTime frame
Expected Outcome Increase in serum BDNF levels, evaluated by ELISA, of at least 5% from the pre to post intervention condition.;Observed Outcome Increase in serum BDNF levels, evaluated by ELISA, greater than 5% from the pre to post intervention condition.—

Countries

Brazil

Contacts

Public ContactElke Bromberg

Pontifícia Universidade Católica do Rio Grande do Sul

bromberg@pucrs.br55 51 33203545

Outcome results

None listed

Source: REBEC (via WHO ICTRP)