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Acute effect of a breath test on heart rate variability and diaphragm muscle mobility in heart transplant recipients

Acute effect of the incremental inspiratory load protocol on a frequency variability and diaphragmatic mobility among adults healthy and heart transplanted

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-3w4xbv
Enrollment
Unknown
Registered
2020-08-20
Start date
2020-02-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart trasnplantation

Interventions

A group of 15 heart transplant patients and 15 healthy individuals will be submitted to evaluations and the incremental inspiratory load test, which will be performed in two days. In order to assess t
Other

Sponsors

Universidade Federal de Pernambuco
Lead Sponsor
Universidade Federal de Pernambuco
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: This study will include adult individuals aged between 18 and 65 years old; of both sexes; who has had heart transplant surgery over a period of 12 months; sedentary; with clinical stability; making regular use of immunosuppressive therapy; no change in medication class within three months prior to the start of the research. Those healthy adult individuals between 18 and 65 years old will be included; sedentary; non smokers; non-drug user; without cardiac involvement.

Exclusion criteria

Exclusion criteria: Patients using pacemakers will be excluded; with HF reactivation or Chagas disease; smoker; alcoholism; using corticosteroids; with obstructive disorder. In addition to patients who present psychological changes that make it impossible to understand the commands required for evaluation. All patients with orthopedic diseases will be excluded; musculoskeletal; neurological or respiratory problems that make it impossible to perform the incremental load test; diabetes; patients who induce dialysis or cardiovascular disease; in addition to patients who have psychic changes that make it impossible to understand the commands required for evaluation.

Design outcomes

Primary

MeasureTime frame
Diaphragmatic mobility in spontaneous breathing and total lung capacity through ultrasound. ;Heart rate variability during an incremental holter test

Secondary

MeasureTime frame
Body composition using the bioimpedance scale ;Submaximal cardiorespiratory capacity, through the 6-minute walk test

Countries

Brazil

Contacts

Public ContactAna Eugênia Vasconcelos do;Daniella Barros;Brandão

Universidade Federal de Pernambuco ;Universidade Federal de Pernambuco

aaninhavasconcelos@gmail.com;daniellacunha@hotmail.com81999208635;+55(81)8135-9335

Outcome results

None listed

Source: REBEC (via WHO ICTRP)