Pulmonary Disease, Chronic Obstructive
Conditions
Interventions
Experimental group: 25 patients with moderate to severe chronic obstructive pulmonary disease (COPD) will be performed exercise training (aerobic and resisted), 2 times/week, 60 minutes/session for 2
Behavioural
G11.427.410.698.277
Sponsors
Hospital das Clínicas da Faculdade de Medicina da USP
Faculdade de Medicina da USP
Eligibility
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients with chronic obstructive pulmonary disease; aged over 50 years; non smokers, of both genders; clinically stable; who have not participated in regular physical training in the last 6 months
Exclusion criteria
Exclusion criteria: Patients with other chronic lung disease; or with rheumatoid arthritis; multiple sclerosis; decompensated diabetes; autoimmune hepatitis; chronic cardiovascular disease; malignant tumor; or with acquired immunodeficiency syndrome - AIDS; use of immunosuppressive drugs; presence of musculoskeletal disorders that make it impossible to perform physical exercise; continuous use of oxygen therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected to find an increase of 2% of anti-inflammatory cells and cytokines, evaluated in peripheral blood by flow cytometry, in chronic obstructive pulmonary disease patients who will perform the exercise training compared to patients who will perform the placebo exercise. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that the increase in anti-inflammatory response is related to the improvement of clinical symptoms and quality of life, assessed through validated questionnaires, of chronic obstructive pulmonary disease patients who will perform the exercise training. | — |
Countries
Brazil
Contacts
Public ContactFernanda Lopes
Hospital das Clínicas da Faculdade de Medicina da USP
Outcome results
None listed