Evaluation of cephalometric changes in Class III Malocclusion patients treated with Maxillary Expansion and Facemask Therapy and their association with respiratory pattern: a randomized clinical trial

Evaluation of airway space, facial type changes, and temporomandibular joint (TMJ) function using cephalometry and magnetic resonance imaging in children with Class III malocclusion treated with two different protocols of maxillary expansion and traction, compared to a control group

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-3vnz34b

Enrollment

Registered

2026-06-02

Start date

2015-04-01

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway Obstruction

Interventions

This is a randomized clinical trial with three arms. A total of 64 Brazilian children and adolescents, aged between 6 and 11 years, with skeletal maturity corresponding to cervical vertebral maturatio

Eligibility

Age

6 Years to 11 Years

Inclusion criteria

Inclusion criteria: Individuals of both genders; with anteroposterior discrepancy between the maxilla and mandible, caused by maxillary retrognathism, mandibular protrusion, or a combination of both, clinically evaluated through facial analysis (nasolabial angle, chin neck line and angle) and cephalometrically through the ANB angle and Witts analysis; with Angle Class III malocclusion or Class III subdivision; with mixed or early permanent dentition; those who underwent orthodontic treatment with maxillary expansion and traction

Exclusion criteria

Exclusion criteria: Individuals with decayed teeth and periodontal compromise; with cleft lip or palate and patients with special needs; those who had not undergone the exams after the treatment or the observation period

Design outcomes

Primary

Measure	Time frame
It is expected to find greater improvement in breathing pattern and airway obstruction in group 2, treated with alternating maxillary expansion and constriction protocol associated with facemask therapy, assssed by anamnesis, clinical examination and nasofibroscopy	—

Secondary

Measure	Time frame
A greater sagittal advancement of the maxilla is expected in Group 2, treated with the Alternate Rapid Maxillary Expansion and Constriction protocol combined with facemask therapy, as assessed by cephalometric analysis	—

Countries

Contacts

Public ContactBruna Florez

Universidade de São Paulo

brunaflorez@hotmail.com+55 (13) 981610203

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Jun 29, 2026