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Efficiency of weight loss support for patients with excess body weight and other diseases that pose a risk to heart health

Effectiveness of a weight loss program for obese patients with cardiovascular risk factors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3vkjyvy
Enrollment
Unknown
Registered
2024-09-19
Start date
2020-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

The population of this cross-sectional study was screened during the nutritional screening consultation, by the researcher herself, at the nutrition outpatient clinic of the Instituto Dante Pazzanese

Sponsors

Instituto Dante Pazzanese de Cardiologia do Estado de São Paulo
Lead Sponsor
Instituto Dante Pazzanese de Cardiologia do Estado de São Paulo
Collaborator

Eligibility

Age
19 Years to No maximum

Inclusion criteria

Inclusion criteria: Being a patient at the Dante Pazzanese Institute of Cardiology-SP; of both genders; be aged = 19 years; agree to participate in the study and have consented and signed the informed consent form

Exclusion criteria

Exclusion criteria: Pregnant patients; patients with liver disease; in the pre-transplant period; diagnosed with chronic kidney disease; oncology, diagnosed with heart failure; atrial fibrillation; with pacemakers and with bundle branch block

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: Participants were expected to achieve a weight reduction of 3.5% of their weight in 3 months of nutritional monitoring. It was expected that this weight reduction would be significant in improving heart rate variability parameters, and that patients would present an improvement in parameters related to quality of life (improvement in sedentary behavior, symptoms related to the risk of depression and quality of diet). ).;Finding outcome 1: 24 patients with obesity (BMI > 30kg/m2) were evaluated, with a mean age of 62 years (min – max: 42 – 80 years, SD: 10 years), 45.8% of whom were adults (5 men and 6 women) and 54.2% elderly (7 men and 6 women). Adherence to healthy eating habits increased on average from 21.3% to 66.5% (P< 0.001). The questionnaire used to assess physical activity demonstrated that, at the end of the study, 88% of patients were classified as physically active when compared to 58% in the baseline period (P=0.023), and there was a significant reduction in the depression risk score after the intervention (Baseline: 8.87 ± 1.15; Post-intervention: 5.15 ± 1.20; P=0.022), indicating improvement in patients' mental health. Significant reductions in the levels of blood glucose, glycated hemoglobin, total cholesterol and the LDLc fraction, and triglycerides were also observed in models adjusted for medication use (P<0.05). The BMI, which before the intervention had an average of 34.8 kg/m2, ranging from 30.0 – 47.4 kg/m2, after the nutritional intervention had an average of 32.6 kg/m2, ranging from 27.7 – 44.8 kg/m2. It was noted that the intervention program was effective in significantly reducing BMI (P=0.029) and waist circumference (P=0.031). An association was identified between the variation in weight loss and decrease in BMI with the variability observed in the components of the frequency domain, both among adult individuals (P=0.003) and among elderly individuals (P=0.034).

Secondary

MeasureTime frame
No secondary outcomes are expected

Countries

Brazil

Contacts

Public ContactPriscila Moreira

Instituto Dante Pazzanese de Cardiologia do Estado de São Paulo

priscila.moreira@unifesp.br+55(11)5085-6080

Outcome results

None listed

Source: REBEC (via WHO ICTRP)