Tooth Demineralization
Conditions
Interventions
This is a randomized clinical trial with three arms: a treatment arm with 30% silver diamine fluoride solution (Cariostop®), a placebo control arm and an alternative treatment arm with chlorhexidine a
Sponsors
Gabriel Magalhães Cairo
Universidade Estadual do Sudoeste da Bahia - UESB
Eligibility
Age
5 Years to 6 Years
Inclusion criteria
Inclusion criteria: Children who have caries activity defined by the presence of at least one active initial lesion will be included (ICDAS-II Scores 1 and 2); no history of allergy to silver, colophonium, fluorine, chlorhexidine, xylitol or vehicles used in cariostatic formulations.
Exclusion criteria
Exclusion criteria: Children who used antibiotics in the last three months will be excluded; who use other systemic medications; who have dental elements with pulp involvement; carriers of syndromes or mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We intend to demonstrate that diamino silver fluoride has a superior performance to the control (placebo) and chlorhexidine combined with xylitol, with significant differences (p value less than or equal to 0.05) not referring to the reduction of scores of the International System of Caries Detection and Assessment (ICDAS-II) among the selection groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to find a reduction in the levels of salivary mutans streptococci with statistically significant differences (p value less than or equal to 0.05) when comparing the group treated with silver diamino fluoride (treatment group), the control group (placebo) and the treatment group with chlorhexidine combined with xylitol (alternative treatment). | — |
Countries
Brazil
Contacts
Public ContactGabriel Cairo
Universidade Estadual do Sudoeste da Bahia - UESB
Outcome results
None listed