Evaluation of respiratory muscle function in patients who underwent Liver Transplantation and are admitted to the Intensive Care Unit

Evaluation of Diaphragmatic function in patients undergoing Liver Transplantation in the Intensive Care Unit

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

REBEC

Registry ID

RBR-3v4k4d6

Enrollment

Registered

2026-03-31

Start date

2025-05-30

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis Liver Transplantation

Interventions

A sample of 15 patients who underwent liver transplantation and were admitted to the TX-ICU at HC-UNICAMP, aged = 18 years, who were still on invasive mechanical ventilation and progressed to successf

Eligibility

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Individuals of both genders, aged between 18 and 70 years, after liver transplantation, admitted to the Adult Intensive Care Unit of the State University of Campinas (Unicamp) will be evaluated. Patients who have undergone liver transplantation and are admitted to the unit still requiring ventilatory support via orotracheal tube and mechanical ventilation and are electively extubated will be considered eligible to participate in the study.

Exclusion criteria

Exclusion criteria: patients who for some reason are re-intubated, that is, need to return to mechanical ventilation, who are not conscious and oriented enough to obey commands and re-liver transplants

Design outcomes

Primary

Measure	Time frame
Surface Electromyography, as well as static (PIMAX) and dynamic assessments of muscle strength using the Powerbreathe® S-Index, are expected to be methods capable of verifying changes in muscle performance (strength, endurance) in patients undergoing LTx and to be able to correlate them with the factors involved throughout the period of hospitalization in the ICU. In addition, this analysis will become important for verifying conducts that prevent these changes and that favor a better quality of life for this population.	—

Measure

Time frame

Surface Electromyography, as well as static (PIMAX) and dynamic assessments of muscle strength using the Powerbreathe® S-Index, are expected to be methods capable of verifying changes in muscle performance (strength, endurance) in patients undergoing LTx and to be able to correlate them with the factors involved throughout the period of hospitalization in the ICU. In addition, this analysis will become important for verifying conducts that prevent these changes and that favor a better quality of life for this population.

—

Secondary

Measure	Time frame
Correlate the factors involved throughout the period of hospitalization in the ICU with the values ??obtained in the tests.	—

Countries

Contacts

Public ContactRayssa Duarte

Hospital de Clinicas da Universidade Estadual de Campinas

rayssa@unicamp.br+55(19)3521-7767

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: May 1, 2026