Type 2 Diabetes Mellitus
Conditions
Interventions
After surveying the patients at the partnering health units, the interested participants will sign the Informed Consent Form, will be classified according to the short version of the International Phy
G11.427.410.698.277
Sponsors
Faculdade de Ciências Médicas de Pernambuco
PPGCS/UPE - Programa de Pós-Graduação em Ciências da Saúde
Eligibility
Sex/Gender
Female
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: Female patients; in the postmenopausal period; diagnosed with type 2 diabetes mellitus; with variations in glycosylated hemoglobin levels less than or equal to 11%; and are classified as being sedentary or irregularly active according to the International Physical Activity Questionnaire.
Exclusion criteria
Exclusion criteria: Past coronary or cerebrovascular event; carriers of chronic kidney disease with an estimated glomerular filtration rate less than or equal to 30 ml / min; orthopedic limitation for physical exercise; proliferative diabetic retinopathy; disabling diabetic neuropathy; NYHA class III or IV heart failure; established liver disease Child B or C classification; decompensated thyroid disease; malignant neoplasm, except for basal cell carcinoma; in coronary, carotid or peripheral arterial revascularization schedule; documented myocardial ischemia; classified as active or very active by the International Physical Activity Questionnaire; participation in any training program using weights in the last 6 months; and with adherence to the systematic resistance training protocol below 80%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1 - Increase in muscle strength, verified by means of handgrip dynamometry, from the observation of a variation of at least 1kg/force in the pre and post intervention measurements.;Expected outcome 2 - Improvement of metabolic indicators: fasting glucose, glycosylated hemoglobin (HbA1c), triglycerides, cholesterol (HDL, LDL and total cholesterol), verified by means of serum dosage (blood test), from the finding of variation in pre and post intervention measures in relation to the reference values for each of the evaluated indicators.;Expected outcome 3 - Improvement in quality of life, verified through the SF-36 quality of life questionnaire, based on the observation of a variation of at least 5% in the values obtained by the questionnaire domain in the pre and post intervention measurements.;Expected outcome 4 - Increase in irisin levels, verified by means of serum dosage (blood test), from the observation of the variation in pre- and post-intervention measurements in relation to the reference values for each of the indicators evaluated.;Expected outcome 5 - High correlation of body composition by Dual Emission X-ray Densitometry (DEXA) and Electrical Bioimpedance (BIA) from pre and post intervention measurements in relation to fat mass, lean mass, and bone mineral mass values obtained through the two methods.;Expected outcome 6 - Increased heart rate variability, verified by means of the 24-hour holter test, from the verification of variation in the pre- and post-intervention measures in relation to the reference values for each of the indicators evaluated. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
Brazil
Contacts
Public ContactLECILDO BATISTA
Outcome results
None listed