Hysterectomy
Conditions
Interventions
This is a randomized controlled clinical trial, double-blind, with 40 participants in each group. The inclusion criteria are: being female, aged between 18 and 65 years
undergoing an abdominal hysterectomy, with or without oophorectomy
having an ASA physical status classification of 1 or 2. The exclusion criteria include: contraindication to any medication used in the study
refusal to participate in the study
refusal of neuroaxial anesthesia
illiteracy. Exclusion criteria cover: perioperative bleeding greater than expected
allergic reaction to any components of the protocol
need for technical changes in surgical or anesthetic procedures during the operation. After ethical approval and registration in the Brazilian Registry of Clinical Trials, participants will be randoml
the control group will receive 15 mg of bupivacaine with 5% glucose, 80 micrograms of morphine, and 0.6 milliliters of 0.9% saline, substituting the clonidine. The anesthetic solution will be prepared
Sponsors
Faculdade de Ciências Médicas e da Saúde da Pontifícia Universidade Católica de São Paulo
Faculdade de Ciências Médicas e da Saúde da Pontifícia Universidade Católica de São Paulo
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: age between 18 and 65 years; woman; underwent abdominal hysterectomy; american society of anesthesiology physical status 1 and 2
Exclusion criteria
Exclusion criteria: illiterate; contraindication to any medication used in the research; refusal to spinal anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The quality of recovery will be assessed using the "Quality of Recovery 15" questionnaire in patients undergoing abdominal hysterectomy under spinal anesthesia, with and without clonidine, between 24 and 36 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| During the intraoperative period, the doses of intraoperative ephedrine and atropine will be assessed, as well as the incidence of heart rates below 60 and 50 beats per minute. In the post-anesthetic recovery room, the dose of morphine administered, the incidence of nausea and vomiting, and the length of stay will be evaluated | — |
Countries
Brazil
Contacts
Public ContactAntonio Moron Morad Neto
Faculdade de Ciências Médicas e da Saúde da Pontifícia Universidade Católica de São Paulo
Outcome results
None listed