Head and Neck Neoplasms
Conditions
Interventions
This study will be divided into 2 objectives:
Objective 1: to evaluate the effect of A-PRF on the healing of post-extraction sockets in pre-radiotherapy patients
Objective 2: to evaluate the effect of A-PRF on the healing of post-extraction sockets in post-radiotherapy patients.
42 patients will be selected for each objective in need of dental extraction.
The
Sponsors
Faculdade de Odontologia da Universidade Federal de Uberlândia
Faculdade de Odontologia da Universidade Federal de Uberlândia
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients diagnosed with head and neck cancer; both genders; age above 18 years; with indication and need for dental extraction either in the pre-radiotherapy or post-radiotherapy phase and who provide consent to participate in this research project by signing the Free and Informed Consent Form
Exclusion criteria
Exclusion criteria: Underage patients, patients who do not agree with the Free and Informed Consent Form; patients with advanced tumors who, due to the urgency of starting radiotherapy, do not have enough time to perform tooth extractions; patients with health changes that contraindicate surgical extraction procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soft tissue healing in the post-extraction region. The clinical evaluation and an evaluation form prepared by the researcher will be used for analysis. This form will include evaluations regarding wound closure, bone exposure and presence of edema, these variables being evaluated by the alternatives YES and No. .As for the presence of bleeding, tissue color, suppuration, color and consistency of the scar tissue, a score scale from 1 to 3 will be used, which will be assigned this grade for each item. This evaluation will be performed after 7, 14, 30, 60 and 90 days postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's pain level, where, to assess, a visual analogue scale will be used, where the participant will assign a value from 0 to 10 regarding the level of pain felt. Another secondary outcome will be the healing of the bone tissue, which will be performed by performing a cone beam computed tomography immediately after the extraction and another tomography performed 90 days after the extraction. | — |
Countries
Brazil
Contacts
Public ContactPriscilla Soares
Faculdade de Odontologia - Universidade Federal de Uberlândia
Outcome results
None listed