Gastroschisis
Conditions
Interventions
Experimental group: 22 newborns with gastroschisis who received colostrum from their mother, in the oral mucosa in the first 48 hours of life until 72 hours of life.
Control group: 22 newborns with g
Other
Sponsors
Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira IFF/ Fiocruz
Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira IFF/ Fiocruz
Eligibility
Inclusion criteria
Inclusion criteria: Newborns; both genres; born with gastroschisis; born in the hospital of origin
Exclusion criteria
Exclusion criteria: Newborns with a maternal history of recent drug use (before hospitalization and delivery); infection with the human immunodeficiency virus (HIV); human T cell lymphotropic virus (HTLV); those who die in the first days of life before completing the oropharyngeal administration protocol; mothers are unable to remove the required volume of colostrum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of colostrotherapy in days to reach oral feeding in newborns with gastroschisis.This intervention proposal will be made through a randomized clinical trial, where patients will be classified to receive either colostrum or placebo for a reason of 1: 1. Based on the specified precision requirements, a minimum sample size of 22 patients in each treatment groups will be needed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analyze the effect of colostrotherapy on zero-diet days.This intervention proposal will be made through a randomized clinical trial, where patients will be classified to receive either colostrum or placebo for a reason of 1: 1. Based on the specified precision requirements, a minimum sample size of 22 patients in each treatment groups will be needed.;Analyze the effect of colostrotherapy in days to start enteral feeding;Analyze the effect of colostrotherapy in days to achieve a full diet;Analyze the effect of colostrotherapy in days on parenteral nutrition;Analyze the effect of colostrotherapy in reducing sepsis;Analyze the effect of colostrotherapy on ? length of stay;Analyze the effect of colostrotherapy in days to start enteral feeding;Analyze the effect of colostrotherapy in days to achieve a full diet;Analyze the effect of colostrotherapy in days on parenteral nutrition;Analyze the effect of colostrotherapy in reducing sepsis | — |
Countries
Brazil
Contacts
Public ContactHellen Pimenta
Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira IFF/ Fiocruz
Outcome results
None listed