Postoperative Pain
Conditions
Interventions
This is a double-blind randomized clinical trial, with patients who will undergo bariatric surgery at the University Hospital Onofre Lopes in the year two thousand and twenty-two, a simple randomizati
Sponsors
Hospital Universitário Onofre Lopes
Hospital Universitário Onofre Lopes
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients undergoing primary (non-revision) bariatric surgeries by videolparoscopy; Physical status American Society of Anesthesiology (ASA) II/III; Age between 18 and 65 years
Exclusion criteria
Exclusion criteria: Revision surgeries or two-stage surgeries; Laparotomy (open) surgeries; Patients with a history of drug addiction; Patients with a history of chronic opioid use; Patients with a history of fibromyalgia or chronic pain; Patients with QT prolongation; Methadone allergy; Creatinine clearance rate below 60ml/min
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Compare side effects such as nausea and vomiting, need for supplemental O2 and respiratory depression between those who received methadone and those who did not;Evaluate reduction in the consumption of rescue analgesics;Compare side effects such as nausea and vomiting, need for supplemental O2 and respiratory depression between those who received methadone and those who did not;Evaluate reduction in the consumption of rescue analgesics | — |
Primary
| Measure | Time frame |
|---|---|
| To assess postoperative pain in patients who received a single dose of methadone during the anesthetic-surgical procedure | — |
Countries
Brazil
Contacts
Public ContactWallace Da Silva
Hospital Universitário Onofre Lopes
Outcome results
None listed