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Study of the acute hand wounds healing using Marigold extract compared to a control group

Comparative study of Healing by second intention in acute traumatic skin injuries in the hand. Calendula officinalis L. Versus Control Group - Second Intention Healing (SIH) Second or Secondary Intention Healing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3sg8mbc
Enrollment
Unknown
Registered
2021-05-27
Start date
2014-02-02
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Injuries

Interventions

Experimental Group: 20 adult individuals who had superficial wounds on the hand and fingers, which occurred due to acute trauma, will receive Calendula officinalis extract to be sprayed on the wound
HP4.018.189.165

Sponsors

Pontificia Universidade Católica do Paraná
Lead Sponsor
Pontificia Universidade Católica do Paraná
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients; with a minimum age of 18 years; attended at the Institution's emergency room for superficial wounds in the hand and fingers; who agreed with the informed consent form; were included. Lesions smaller than 10 cm2 (1000 mm2) were inserted in which the second intention was the initial option of the medical assistent. Option based on the loss of tissue due to trauma or the impossibility of complete primary closure of the edges of the wound and without exposure of bone; nerve; vessels or tendons.

Exclusion criteria

Exclusion criteria: Patients with clinical signs of infection; who did not adhere to the treatment with evidence of inadequate hygiene of the lesion; in disagreement with medical advice; abandonment of treatment; development of an adverse reaction to the products used in both groups; were excluded from the study.

Design outcomes

Primary

MeasureTime frame
Regarding the outcome, wound healing speed was found in the group treated with Marigold extract with a speed of 3.328 higher than in the control group treated with mineral oil.;It is expected that the healing rate of acute traumatic skin lesions in the hand and fingers treated with Marigold extract will be greater than that observed in the control group lesions verified through planimetry with photodocumentation.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactGiana Giostri

Pontificia Universidade Católica do Paraná

ggiostri@gmail.com+5541991126896

Outcome results

None listed

Source: REBEC (via WHO ICTRP)