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Rabies prevention: assessing the effect and cost of three (03) vaccination strategies

Rabies pre-exposure prophylaxis: Cost-effectiveness analysis of three (03) vaccination strategies

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-3s36zh
Enrollment
Unknown
Registered
2019-08-23
Start date
2019-08-26
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contact with exposure to rabies

Interventions

Anti-rabies vaccination in 3 groups of participants chosen through randomization. Group 1: 100 participants will receive three (3) doses of intramuscular vaccine (MI) on days 0, 7 and 28 (Ministry of
Biological/vaccine
D20.215.894.899.700
Z24.2

Sponsors

Fundação Oswaldo Cruz
Lead Sponsor
Fundação Oswaldo Cruz
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Travelers; veterinarians; other professionals with occupational risk of exposure to rabies virus over the age of 18 years

Exclusion criteria

Exclusion criteria: Pre-or post-exposure rabies vaccine use; Severe allergy reported to any component of the vaccine; reported pregnancy; Disability to attend study visits; Abuse of illicit substances; Moderate to severe psychiatric illness; Immunosuppressive disease; Use of immunosuppressant medication for any reason within six (06) months prior to the study inclusion visit

Design outcomes

Primary

MeasureTime frame
Evaluate which rabies pre-exposure prophylaxis scheme is most cost effective—

Secondary

MeasureTime frame
No Secondary Outcomes Expected—

Countries

Brazil

Contacts

Public ContactMarcellus Costa

Fundação Oswaldo Cruz

marcellus.costa@ini.fiocruz.br+55(21)38659124

Outcome results

None listed

Source: REBEC (via WHO ICTRP)