Sedentary Lifestyle
Conditions
Interventions
Experimental Groups:
High-intensity interval training (35 subjects): Eight weeks of cycling, 40 min/day, 3-4 times/week at 50-90% of heart rate reserve
Continuous endurance training (35 subjects): Eight weeks of cycling, 40 min/day, 3-4 times/week at 70-75% of heart rate reserve
Controle (12 subjects): Eight weeks without any exercise program
Other
G11.427.410.698.277
Sponsors
Faculdade de Educação Física da Universidade Estadual de Campinas
Laboratório Nacional de Biociências - LNBio
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Young sedentary healthy men; age between 18-30 years old
Exclusion criteria
Exclusion criteria: Smokers; hypertensive with systolic blood pressure higher than 140 and diastolic blood pressure higher than 90 mm Hg; diabetic with fasting glucose higher than 7.0 mmol L-1; severe obese defined defined as body mass index higher than 33 kg m-2; dyslipidemic based on medication; com evidence of heart diseases; metabolic disorders; significant chronic respiratory conditions or musculoskeletal problems interfering with exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome is the change in the cardiorespiratory fitness in response to training, which will be measured by the maximal oxygen uptake (ml/min) and maximal power output (W) performed during incremental test until exhaustion, pre and post 8-weeks training program | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum and skekeletal metabolite levels (mmol) analyzed by metabolomics . These metabolites will be used to the understanding of mechanisms associated to variation on main outcome (cardiorespiratory fitness) in response to training programs;Changes on body composition, measured by na composição corporal, mensurada by plethysmograph for analysis of fat-free mass and fat mass in kilograms (kg) and percentages (%) pre and post 8-weeks training program;Changes in lipid profile (total cholesterol, triglycerides, HDL, LDL, VLDL em mg/dL) pre and post 8-weeks training program;Changes in cardiac autonomic modulation measured by the heart rate variability using heart rate monitor (POLAR). Analysis will be performed on time domain (iRR, RMSSD e SDNN, in ms, and pNN50 em %) and frequency domain (LF, HF, VLF, LF/HF, TP, em ms2 e n.u.) pre and post 8-weeks training program | — |
Countries
Brazil
Contacts
Public ContactAlex;Mara Castro;Chacon-Mikahil
Faculdade de Educação Física da Universidade Estadual de Campinas;Faculdade de Educação Física da Universidade Estadual de Campinas
Outcome results
None listed