Malaise and fatigue
Conditions
Interventions
This is a randomized controlled clinical (RCT), unmasked, trial to evaluate the impact of physical activity on serum adiponectin levels in women undergoing neoadjuvant chemotherapy for breast cancer.
I03.350
Sponsors
Hospital das Clínicas Universidade Federal de Goiás
Hospital das Clínicas Universidade Federal de Goiás
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years old; not having started any cycle of chemotherapy; diagnosis of breast carcinoma confirmed by histopathological; being sedentary, having not exercised for at least 6 months
Exclusion criteria
Exclusion criteria: Patients with cognitive impairment or neurological diseases; patients with osteoarticular injuries that prevent physical activity; patients with previous malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of physical activity on serum adiponectin levels and neuromuscular and cardiorespiratory parameters, body composition and cellular integrity in women with breast cancer, during neoadjuvant chemotherapy (before and after chemotherapy). It is expected that results will be improved in groups that perform physical exercise. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlate serum adiponectin levels with breast cancer subtypes. Higher levels of adiponectin are expected in tumors with a better prognosis. ;Higher serum adiponectin levels are expected in patients who had a higher response rate ;To evaluate supervised physical training on the response rate of neoadjuvant breast cancer treatment through specific training parameters. | — |
Countries
Brazil
Contacts
Public ContactVictor Rosa
Hospital das Clínicas Universidade Federal de Goiás
Outcome results
None listed